Tsuda S, Pipkin ME
Transcriptional Control of Cell Fate Determination in Antigen-Experienced CD8 T Cells.
Cold Spring Harb Perspect Biol. 2021 Jun 14;a037945. doi: 10.1101/cshperspect.a037945. PMID: 34127445.

Xu T, Schutte A, Jimenez L, Gonçalves ANA, Keller A, Pipkin ME, Nakaya HI, Pereira RM, Martinez GJ.
Kdm6b Regulates the Generation of Effector CD8 + T Cells by Inducing Chromatin Accessibility in Effector-Associated Genes.
J Immunol. 2021 May 1;206(9):2170-2183. doi: 10.4049/jimmunol.2001459. Epub 2021 Apr 16. PMID: 33863789.

Chen ML, Huang X, Wang H, Hegner C, Liu Y, Shang J, Eliason A, Diao H, Park H, Frey B, Wang G, Mosure SA, Solt SA, Kojetin DJ, Rodriguez-Palacios A, Schady DA, Weaver CT, Pipkin ME, Moore DD, Sundrud MS.
CAR directs T cell adaptation to bile acids in the small intestine.
Nature. 2021 April 7. doi: 10.1038/s41586-021-03421-6. PMID: 33828301.

Pipkin ME.
Runx proteins and transcriptional mechanisms that govern memory CD8 T cell development.
Immunol Rev. 2021 Mar;300(1):100-124. doi: 10.1111/imr.12954. Epub 2021 Mar 7.PMID: 33682165 

Choi J, Diao H, Faliti CE, Truong J, Rossi M, Bélanger S, Yu B, Goldrath AW, Pipkin ME, Crotty S. 
Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits.
Nat Immunol. 2020 Jul;21(7):777-789. doi: 10.1038/s41590-020-0706-5. Epub 2020 Jun 22. PubMed PMID: 32572238.

Chen ML, Sun A, Cao W, Eliason A, Mendez KM, Getzler AJ, Tsuda S, Diao H, Mukori C, Bruno NE, Kim SY, Pipkin ME, Koralov SB, Sundrud MS. 
Physiological expression and function of the MDR1 transporter in cytotoxic T lymphocytes
J Exp Med. 2020 May 4;217(5):e20191388. doi: 10.1084/jem.20191388. PMID: 32302378; PMCID: PMC7201929.1388

Diao H, Pipkin ME
Stability and flexibility in chromatin structure and transcription underlies memory CD8 T-cell differentiation. 
F1000Res. 2019;8:F1000 Faculty Rev-1278. Published 2019 Jul 31. doi: 10.12688/f1000research.18211.1

Wang D,  Diao H, Getzler AJ, Rogal W, Frederick MA, Milner JJ, Yu B, Crotty S, Goldrath AW, Pipkin ME.
The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation.
Immunity. 2018 April 17;48(4):659–674. doi: 10.1016/j.immuni.2018.03.028.

Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW.
Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours.
Nature. 2017 Dec 14;552(7684):253-257. doi: 10.1038/nature24993. Epub 2017 Dec 6.

Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW.
Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation.
Nat Immunol. 2017 May;18(5):573-582. doi: 10.1038/ni.3706. Epub 2017 Mar 13.

Crotty S, Pipkin ME.
In vivo RNAi screens: concepts and applications.
Trends Immunol. 2015 May;36(5):315-22. doi: 10.1016/ Epub 2015 Apr 27. Review.

Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, Rao A.
The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.
Immunity. 2015 Feb 17;42(2):265-278. doi: 10.1016/j.immuni.2015.01.006. Epub 2015 Feb 10.

Chen R, Bélanger S, Frederick MA, Li B, Johnston RJ, Xiao N, Liu YC, Sharma S, Peters B, Rao A, Crotty S, Pipkin ME.
In vivo RNA interference screens identify regulators of antiviral CD4(+) and CD8(+) T cell differentiation.
Immunity. 2014 Aug 21;41(2):325-38. doi: 10.1016/j.immuni.2014.08.002.

Trifari S, Pipkin ME, Bandukwala HS, Äijö T, Bassein J, Chen R, Martinez GJ, Rao A.
MicroRNA-directed program of cytotoxic CD8+ T-cell differentiation.
Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18608-13. doi: 10.1073/pnas.1317191110. Epub 2013 Oct 25.

Yigit E, Zhang Q, Xi L, Grilley D, Widom J, Wang JP, Rao A, Pipkin ME.
High-resolution nucleosome mapping of targeted regions using BAC-based enrichment.
Nucleic Acids Res. 2013 Apr;41(7):e87. doi: 10.1093/nar/gkt081. Epub 2013 Feb 14.

Pipkin ME.
Memories in the snow: immune memory, persistent infection and chronic disease.
EMBO Rep, Jul 1;12(7):617-9.

Pipkin ME, Sacks JA, Cruz-Guilloty F, Lichtenheld MG, Bevan MJ, Rao A.
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.
Immunity. 2010 Jan 29;32(1):79-90. doi: 10.1016/j.immuni.2009.11.012. Epub 2010 Jan 21.

Cruz-Guilloty F, Pipkin ME, Djuretic IM, Levanon D, Lotem J, Lichtenheld MG, Groner Y, Rao A.
Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs.
J Exp Med. 2009 Jan 16;206(1):51-9. doi: 10.1084/jem.20081242. Epub 2009 Jan 12.

Pipkin ME, Ljutic B, Cruz-Guilloty F, Nouzova M, Rao A, Zúñiga-Pflücker JC, Lichtenheld MG.
Chromosome transfer activates and delineates a locus control region for perforin.
Immunity. 2007 Jan;26(1):29-41. Epub 2007 Jan 11.

Pipkin ME, Lichtenheld MG.
A reliable method to display authentic DNase I hypersensitive sites at long-ranges in single-copy genes from large genomes.
Nucleic Acids Res. 2006 Mar 1;34(4):e34.

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